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Mother-of-two Pamela, who was also wed to rockers Tommy Lee and Kid Rock, revealed in October 2013 that she and Rick were 'friends with benefits', confirming three months later that the pair had remarried on an unspecified date.
“This whole area seems to have been populated by very small groups of people making it across these stepping-stone islands, so you do have very dramatic effects in fluctuations of gene frequency.” It is absolutely correct that Oceanian populations exhibit a lot of evidence of small effective population, and so are subject to random genetic drift.
In this model the frequency of ~0.25 for the allele which results in bondlism in the homozygote in the Solomon islands is high as it is due to a drift event up in frequency from an initial variant mutation. The first is a somewhat technical one: if the high frequency in the Solomons is due to rapid rise in frequency due to large generation-to-generation fluctuations, you’d expect to see some linkage disequilibrium in the region of .
If the drift event occurred in the past, the allele should be fixed, or, it should be extinct.
If you imagine that it was fixed in some populations, and then admixture resulted in the allele segregation, then there should be LD around the SNP too.
Here, we identify an arginine-to-cysteine change at a highly conserved residue in tyrosinase-related protein 1 (TYRP1) as a major determinant of blond hair in Solomon Islanders.
This missense mutation is predicted to affect catalytic activity of TYRP1 and causes blond hair through a recessive mode of inheritance. They looked at variants in a lot of people with the trait, vs. Additionally, if you check the supplements and read the text it’s obvious there is no population straification.
Even if it wasn’t a selective sweep, flanking SNPs would still be transmitted at high frequency with the causal variant through drift.It is noted in the text that the authors did not find evidenc of high LD in their tests for natural selection, XP-EHH or i HS.These tests are cued to pick up relatively recent selective events, on the order of ~10,000 years or so.Another aspect of the phenotype was also straightforward: it did not seem that light hair color resulted in any concomitant lightening of the skin.Granting that this was a heritable biological trait, the questions then were simple: was this trait an independent occurrence of de-pigmentation in Oceania, or was it due to introgression of European alleles?