Cannabidiol (CBD) can help treat seizures, can reduce anxiety and paranoia, and can counteract the "high" caused by THC. Different cultivars (strains or types) and even different crops of marijuana plants can have varying amounts of these and other active compounds. Oromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial. Relying on marijuana alone as treatment while avoiding or delaying conventional medical care for cancer may have serious health consequences. While the most common effect of marijuana is a feeling of euphoria ("high"), it also can lower the user’s control over movement, cause disorientation, and sometimes cause unpleasant thoughts or feelings of anxiety and paranoia. Smoked marijuana delivers THC and other cannabinoids to the body, but it also delivers harmful substances to users and those close by, including many of the same substances found in tobacco smoke. There have been some early clinical trials of cannabinoids in treating cancer in humans and more studies are planned. Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting. While the studies so far have shown that cannabinoids can be safe in treating cancer, they do not show that they help control or cure the disease. Dronabinol has also been found to help improve food intake and prevent weight loss in patients with HIV. Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. In studies of cancer patients, though, it wasn’t better than placebo or another drug (megestrol acetate).
Smoked marijuana has also helped improve food intake in HIV patients in studies. Nabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized, placebo-controlled, graded-dose trial. Different compounds in marijuana have different actions in the human body. For example, delta-9-tetrahydrocannabinol (THC) seems to cause the "high" reported by marijuana users, and also can help relieve pain and nausea, reduce inflammation, and can act as an antioxidant. Flavonoid glycosides and cannabinoids from the pollen of Cannabis sativa L. Marijuana is the name given to the dried buds and leaves of varieties of the Cannabis sativa plant, which can grow wild in warm and tropical climates throughout the world and be cultivated commercially. It goes by many names, including pot, grass, cannabis, weed, hemp, hash, marihuana, ganja, and dozens of others. Low-dose vaporized cannabis significantly improves neuropathic pain.