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Cri du chat syndrome, also known as chromosome 5p deletion syndrome, 5p− syndrome (pronounced "Five P Minus") or Lejeune’s syndrome, is a rare genetic disorder due to chromosome deletion on chromosome 5.

The syndrome gets its name from the characteristic cry of affected infants, which is similar to that of a meowing kitten, due to problems with the larynx and nervous system.

You can also make a JSONP request, have it received as text, and interpreted by j Query as XML: "jsonp text xml." Similarly, a shorthand string such as "jsonp xml" will first attempt to convert from jsonp to xml, and, failing that, convert from jsonp to text, and then from text to xml.

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About 1/3 of children lose the cry by age of 2 years.

Other symptoms of cri du chat syndrome may include: Other common findings include hypotonia, microcephaly, growth retardation, a round face with full cheeks, hypertelorism, epicanthal folds, down-slanting palpebral fissures, strabismus, flat nasal bridge, down-turned mouth, micrognathia, low-set ears, short fingers, single palmar creases, and cardiac defects (e.g., ventricular septal defect [VSD], atrial septal defect [ASD], patent ductus arteriosus [PDA], tetralogy of Fallot). It has also been observed that people with the condition have difficulties communicating.

The remaining 10-15% are due to unequal segregation of a parental balanced translocation where the 5p monosomy is often accompanied by a trisomic portion of the genome.

These individuals may have more severe disease than those with isolated monosomy of 5p.

Il 90% delle delezioni de novo si genera sul cromosoma di derivazione paterna.I sintomi e i fenotipi che ne derivano dipendono dal frammento cromosomico deleto, in particolare il "pianto del gatto" mappa nella regione 5p15.3, mentre le caratteristiche facciali mappano in una regione più prossimale, 5p15.2.La regione 5p15.2 è considerata la regione critica della sindrome.I changed to data Type:'jsonp' added jsonp:'callbackname'.Because j Query by default calls the callback parameter callback, but e Bay expect it to be called 'callbackname'.

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